Victoria Capapé Poves (2014)

The clinical aim was to avoid the arterial clamping during laparoscopic partial nephrectomy (LPN) by means of an RF electrode (Coolinside) which cuts and coagulates simultaneously the parenchyma. For this purpose, we conducted an experimental study based on a porcine model in which LPN with standard technique was compared to NLP with Coolinside and closure of the collecting system. After 21 days, a leakage test was conducted with methylene blue. Urine and blood samples were also collected during the survival period.
We observed that operative time was shorter with Coolinside. No differences in the intraoperative blood loss were found. A higher incidence of leakage was observed with Coolinside; however this was not associated with a higher presence of localized urinary extravasation (urinoma). The postoperative clinical progress was also similar in both groups. We did not find differences between groups in the analytical parameters associated with acute renal failure.
We conclude that NLP with Coolinside is as safe as standard NLP, and it could be a good option for exophytic lesions that do not extensively involve the urinary collecting system.